Pregabalin Capsules

Pregabalin – An Introduction

Pregabalin, sold under the brand names Nervigesic and Lyrica, among others, is an FDA-approved medication with numerous uses such as fibromyalgia, seizure, and neuropathic pain.

Pregabalin is a Schedule V  controlled substance, which means it has a very low risk of abuse. In 2004, it was the 73rd most prescribed medicine in the US [1].

Pregabalin Capsules Uses

There are various FDA-approved and off-label (not approved by the FDA) uses of Pregabalin.

5 FDA-approved uses of Pregabalin:

• Treatment of neuropathic pain associated with spinal cord injury.
• Treatment of fibromyalgia ( a long-term condition that causes tenderness and pain in the whole body)
• Neuropathic pain originating from postherpetic neuralgia (pain that persists after shingles blisters have cleared up).
• Treatment of neuropathic pain associated with diabetic peripheral neuropathy (a type of nerve damage associated with diabetes).
• Adjunctive therapy for partial-onset seizures in adults with epilepsy.

7 off-label indications:

• Generalized anxiety disorder – a chronic state of severe tension and worry impacting everyday life.
• Bipolar disorder – a mental health disorder characterized by periods of depression and periods of abnormally elevated mood.
• Social anxiety disorder – a mental health condition that causes anxiety and fear when you’re around people in social situations.
• Insomnia
• Restless leg syndrome – Restless leg syndrome is a condition in which a person feels a strong urge to move their legs.
• Chronic pain conditions
• Chronic Pruritus – itching lasting for 6 weeks or more  [2].

Benefits Of Pregabalin

Pregabalin provides four main benefits including –

• Pregabalin is beneficial in treating chronic (long-term) pain caused by nerve damage associated with spinal cord injury, diabetes, and shingles.
• It is effective in treating the symptoms of various mental health disorders such as generalized anxiety disorder, bipolar disorder, and social anxiety disorder.
• The therapeutic effects of Pregabalin have been proven effective in treating seizures (fits).
• Taking Pregabalin improves social and physical functioning and overall quality of life.

Pregabalin Dosage

WebMD recommends taking the prescribed dosage of pregabalin 2 to 3 times daily. The dosage is based on several factors, such as the severity of your conditions, age, and response to your treatment.

Comparison Between Different Dosage Strengths

In this section, we will be discussing the available dosage strengths of Nervigesic (a popular brand name for Pregabalin).

Nervigesic is available in the dosage strengths of 75 mg, 150 mg, and 300 mg. Nervigesic 75 mg is ideal for beginners and is used to relieve anxiety and nerve pain whereas Nervigesic 150 mg is prescribed as maintenance therapy (a type of therapy designed to help a primary treatment succeed), fibromyalgia, and moderate pain. The highest dosage strength of this drug is Nervigesic 300 mg which is used for severe neuropathic pain and is suitable for the chronic management of complex conditions.

Directions To Use

It is crucial to take Pregabalin in the right way to avoid any unwanted effects from the medication. The proper way to consume this medicine is as follows –

• Place the Nervigesic tablet in your mouth and swallow the whole medication with water or other oral fluids.
• Chewing, breaking, or crushing the Pregabalin tablets is not advisable.
• Follow all the administration guidelines of your health care provider.
• Try to take Pregabalin at the same time every day.

Pregabalin Overdose

Taking Pregabalin capsules more than the recommended dosage can lead to drug overdose.

Symptoms of a pregabalin overdose include – anxiety or depression, confusion, seizures, excessive sleepiness or drowsiness, and feeling agitated or restless.

Pregabalin Withdrawal

In a few cases, Pregabalin can cause physical dependence and withdrawal symptoms if used for a prolonged period of time. Long-term Pregabalin abuse can cause physical and psychological dependence on the effects of the drug, resulting in withdrawal symptoms.

The symptoms of pregabalin withdrawal can differ in type and severity, depending on individual factors such as the duration and dosage of Pregabalin use and the individual’s overall health. It is important to remember that not everyone who stops taking the anticonvulsant medication will experience withdrawal symptoms.

11 common Pregabalin withdrawal symptoms include –

• Irritability
• Headaches
• Nausea or vomiting
• Increased heart rate
• Suicidal thoughts
• Seizures
• Muscle pain
• Mood swings
• Anxiety
• Insomnia
• Dizziness

Pregabalin Warnings – Things To Remember

Consider these four precautionary measures while taking Pregabalin tablets –

• If you suffer from severe allergic reactions after taking Pregabalin, stop taking the medication and seek medical help.
• Pregabalin is detected in the milk of lactating mothers, therefore breastfeeding women should avoid the use of this anticonvulsant.
• Do not take Pregabalin and alcohol together because they can cause excessive drowsiness and could even develop breathing difficulties in severe cases.
• Older people may be more sensitive to the unwanted effects of this medicine. Therefore, closely monitor older adults while they are on Pregabalin.

Side Effects

Every medicine comes with some sort of side effects so does Pregabalin.

The 7 most common side effects of Pregabalin include [3] –

• Dizziness
• Trouble concentrating
• Dry mouth
• Weight gain
• Swelling of your feet or  hands
• Blurred vision
• Sleepiness.

Serious side effects include –

• Serious allergic reactions can include swelling of your lips, gums, tongue, throat, neck, face, or mouth.
• Suicidal thoughts and signs can include depression, suicide attempts, panic attacks, insomnia, irritability, episodes of mania, new or worsened irritability, and acting angry, aggressive, or violent.
• Fluid retention, symptoms include chest pain.

In the event of any serious side effects after taking Pregabalin seek emergency medical help.

Pregabalin Interactions – What should not be taken with pregabalin?

Pregabalin is known to interact with a total of 283 drugs, out of which 28 are major, 254 are moderate, and 1 is minor [4].

Note – Before taking any medication while taking Pregabalin it is essential to talk to a doctor or pharmacist first to avoid unwanted reactions.

How To Buy Pregabalin From Vedi Care Health?

Vedi Care is a leading Indian-based digital healthcare platform that sells genuine ED and pain medications at free shipping and affordable rates.

Follow the following steps to order Nervigesic (brand version of Pregabalin) from Vedi Care –

• Open vedicarehealth.com.
• From the navigation bar click on the pain medication option.
• After clicking on the pain medication option from the navigation bar you’ll see a list of pain meds listed on the left side of the page.
• Then, select the dosage strength according to your requirements.
• After selecting the dosage strength, select the quantity of pills and click on the ‘add to cart’ option.
• Then click the proceed to checkout option and provide all your necessary contact details such as address and phone number.
• Place your order and you’ll get a payment link on your mail address.
• Click on the payment link and complete your payment.
• After the successful completion of your payment, you will get an order confirmation mail where you’ll get your tracking number.
• You can track your order with the tracking number.

Conclusion

In conclusion, Pregabalin is a powerful medicine that has been shown to be effective in treating numerous health ailments. However, it is important to use Pregabalin with caution due to its potential side effects.

Therefore, by staying well informed and communicating with healthcare professionals, patients can make informed decisions about their treatment with Pregabalin.