Tapentadol is a strong pain medication used to treat moderate to severe body pain. It is a safe medication if used as prescribed. However, this pain medicine can have potentially dangerous interactions with other substances, including alcohol. In some scenarios, these interactions can lead to medical emergencies. If you take Tapentadol, it’s crucial to understand why you should avoid mixing this medicine with alcohol.
Can I Combine Alcohol And Tapentadol?
No, it is not recommended to take Tapentadol and alcohol together because it can cause various side effects. If you have any questions related to alcohol and Tapentadol use, consult your healthcare provider [1].
Tapentadol, when taken after consulting a doctor and without coadministrating them with other medications and substances, is very potential to manage acute and chronic pain within 30 minutes. Explore a wide range of Tapentadol brand drugs by visiting our category page – Tapentadol.
Risks Of Mixing Alcohol And Tapentadol
Some of the risks associated with mixing Tapentadol and alcohol are [2] –
Increased Sedation –
Individually, both Tapentadol and alcohol can induce sedation. When coadministered, they can have additive or synergistic effects that amplify each other. This can cause severe sleepiness, impaired cognitive and motor functions, confusion, and reduced coordination, which increases the chances of accidents, injuries, falls, and other hazards.
Increased risk of overdose –
Tapentadol has a narrow therapeutic index, which means the difference between a toxic dose and a therapeutic dose is relatively small. It doesn’t take much more than the prescribed dose of Tapentadol to reach toxic levels in the body.
When consumed with alcohol, which enhances the sedative effects of Tapentadol, it even seems easier to reach concentration levels that are overwhelming to the body. This, as a result, could lead to life-threatening negative effects, including seizures, cardiac arrest, and coma.
Respiratory depression –
Both alcohol and Tapentadol can depress the respiratory system. Respiratory depression can cause shallow breathing and does not provide enough oxygen to the brain. When alcohol and Tapentadol are used together, these effects can intensify further, leading to severe respiratory depression that can lead to unconsciousness and life-threatening complications.
Disrupted absorption of Tapentadol –
The presence of alcohol in the system can interfere with the absorption, distribution, metabolism, safety, and efficacy, altering its pharmacokinetics. Both alcohol and Tapentadol are metabolized in the liver, which adds extra strain and increases the risk of liver damage.
How Long After Taking Tapentadol Can I Drink Alcohol?
To drink alcohol after taking Tapentadol, it is crucial to wait for tapentadol to leave your system. The amount of time required for Tapentadol to leave the system varies from person to person based on various factors like age, dosage, liver and kidney function, etc.
Get a quick look at our blog page, “How long does Tapentadol stay in your system?“” to better understand its metabolic activity and its elimination time in our body.
To be safe, you should speak to a healthcare provider to determine the appropriate waiting period based on your individual situation and the amount of Tapentadol you’ve consumed.
Other Interactions Of Tapentadol
Taking Tapentadol with other medications or supplements can lead to drug interaction. This can lower the effectiveness and increase the risk of side effects of Tapentadol.
Some of the medications that should be avoided with Tapentadol include –
Major drug interaction | Moderate drug interaction |
Clomipramine | Methsuximide |
Halazepam | Dobutamine |
Naltrexone | Stiripentol |
Flurazepam | Ezogabine |
Gabapentin | Clidinium |
Pimozide | Levalbuterol |
Lorcaserin | Apomorphine |
Doxepin | Flavoxate |
Warnings And Precautions
- Inform your doctor if you are pregnant. Tapentadol may cause life-threatening withdrawal symptoms in an infant if the mother has taken this pain medication during pregnancy.
- Tapentadol may be habit-forming. Take this medicine exactly as prescribed by your healthcare provider.
- Tapentadol should not be used by people with severe asthma, breathing problems, or other lung issues.
- Tapentadol should be taken cautiously by elderly people since the risk of severe side effects in this population is significantly high.
- Tapentadol should not be used in children below 18 years of age due to the lack of safety and efficacy data [3] [4].
Tapentadol And Alcohol – Our Final Thought
The combination of alcohol and Tapentadol can have serious consequences, such as respiratory depression, increased risk of overdose and sedation, and disrupted absorption of Tapentadol.
Avoid alcohol, follow your prescribed dosage, and talk to a healthcare provider for any concerns. Following these steps, you can effectively manage pain with Tapentadol without any adverse effects.
FAQs
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References
- Tapentadol (Palexia®), christie.
- Combining Tapentadol & Alcohol | What Are The Dangers? Bicyclehealth.
- Tapentadol, drugs
- Nucynta (tapentadol) - Uses, Side Effects, and More, WebMd