Aspadol 100 mg is a centrally-acting opioid pain medication that is well known for its therapeutic benefits. In order to guarantee the efficient and safe use of this medication, both healthcare providers and patients must be mindful of its potential side effects.

This blog takes a look into some of the common and serious side effects of opioid pain medication to help you avoid and manage them effectively.

A Brief Introduction To Aspadol 100 Mg

Aspadol 100 mg is an opioid pain medication that treats chronic or severe pain. This medication is composed of the active ingredient Tapentadol hydrochloride. Tapentadol is also sold under other brand names, such as Nucynta, Tapaday, and Topcynta, among others. This pain medication was approved for use in the United States in 2008 [1].

The use of this medicine includes managing body pain linked to arthritis, fibromyalgia, and diabetic neuropathy. It is available in immediate-release (IR) and extended-release (ER) formulations.

Aspadol 100 mg immediate-release tablets are those that disintegrate rapidly, whereas extended-release tablets are designed to release a drug over a prolonged period of time after the dose is administered.

Get a detailed overview of the pain medication by visiting our page, Aspadol 100 mg today.

Common Side Effects Of Aspadol 100 Mg

The most common adverse events noted with Aspadol IR and ER formulations were [2]

Vomiting or Nausea

Nausea and vomiting sometimes occur on the first or second day of taking Aspadol.

A study stated that nausea occurs in up to 40% of people taking opioids, and vomiting occurs in up to 25% of individuals [3].

Aspadol causes nausea in different ways. They slow food movement through the digestive tract and activate an area of the brain that causes nausea and vomiting.

Constipation

Constipation is a common side effect of Aspadol. In fact, in long-term opioid treatment, constipation is the most common adverse event. One may have constipation immediately after taking Aspadol, or it can develop after you’ve been taking it for a while.

Dizziness

Aspadol can cause dizziness in some people due to its effects on the brain. If you’re suffering from dizziness after taking Aspadol, do not do activities that require alertness, like driving.

Drowsiness

Sometimes, Aspadol can cause drowsiness on the first day or so after taking the medicine or after a dose is increased. If you only take this medication before bedtime, this side effect may not bother you.

Headache

Aspadol can cause dehydration, which might contribute to headaches. Headaches caused by this opioid pain medication can vary from individual to individual. Generally, this side effect of Aspadol might start shortly after beginning the medicine, often within a few hours to a day.

Pruritis (itchy skin)

Aspadol 100 mg can cause itchiness. This medicine triggers itchiness by a type of immune system cell known as the mast cells to release histamine. Histamine is a chemical present in the body that contributes to allergic symptoms, including itchy skin.

Less Common Side Effects Of Aspadol 100 Mg

Less common side effects of Aspadol 100 mg are [4] –

• Chills
• Cough
• Fever
• Loss of voice
• Muscle aches
• Unusual tiredness or weakness
• Bladder pain
• Bloody or cloudy urine
• Burning or painful urination
• Unusual tiredness or weakness.

Rare Side Effects Of Aspadol 100 Mg

Seizures, slurred speech, anxiety, trouble swallowing, chest tightness, swelling of the face, tongue, lips, pale or blue lips, fingernails, skin, and shakiness are some of the serious and rare side effects of this pain medication.

Although these adverse events occur rarely, if they do, it is advised to consult a health care provider immediately.

Long-Term Side Effects Of Aspadol

Aspadol 100 mg is known to cause two problems in people who keep taking this medication for long periods of time [2].

• Risk of Overdosing
• Withdrawal

Signs of Aspadol Overdose

Symptoms of Aspadol overdose are – Sweating, confusion, clammy skin, slowed breathing, drowsiness, blurred vision, and muscle weakness.

Other signs include – cardiac arrest, snoring caused by shallow breathing, limp or stiff muscles, coma, low blood pressure, and extremely slow heart rate [5].

Withdrawal Symptoms

If a person continues taking Aspadol 100 mg for a longer duration, especially at higher doses, physical dependence can lead to addiction. Once an individual develops physical dependence on Tapentadol and attempts to quit the medication or reduce its dosage, they’re likely to suffer from Aspadol withdrawal symptoms.

The most common withdrawal symptoms of Aspadol 100 mg are – increased blood pressure, runny nose, restlessness, sweating, diarrhea, anxiety, difficulty falling or staying asleep, stomach ache, vomiting, nausea, breathing difficulties, shivering, goosebumps, tremors, hallucinations, increased heartbeat, blurry vision, and muscle aches [6].

Notable Side Effects of Aspadol ER Tablets

The adverse events associated with Aspadol IR tablets are almost similar to those of its ER formulation. Still, here is a list of the possible side effects of Aspadol ER formulation that one should know before taking the medication.

• Allergic reactions – itching, hives, and rash.
• CNS depression – feeling faint, dizziness, shortness of breath, slow or shallow breathing, confusion, and trouble staying awake.
• Low blood pressure – dizziness, feeling faint or lightheaded, and blurry vision.
• Similar to immediate-release formulation, it can also cause headache, nausea, and constipation [7].

Managing The Side Effects Of Aspadol 100 Mg

Some of the effective ways to manage the side effects of Aspadol 100 mg are –

Talk to your healthcare provider –

People with kidney and liver problems should consult a healthcare professional before taking Aspadol 100 mg. This is because such people are more prone to the side effects of this drug.

Take Precautions

• Do not take other medicines with Tapentadol to avoid drug interaction.
• Pregnant and breastfeeding women should always consult a doctor before taking Aspadol 100 mg.

Adopt Tapering-off Method

To avoid Aspadol withdrawal symptoms, follow a taping-off method. Follow the prescribed dosage of Aspadol 100 mg, then gradually reduce the dosage of the medication, allowing the body to adjust.

Conclusion

Individual variation play a role in how people may experience side effects from Aspadol 100 mg. Factors such as dosage, duration of use, drug interactions, and pre-existing medical conditions can influence the severity and likelihood of side effects.

It is important to consult a doctor before starting Aspadol to assess the appropriateness and discuss any potential risks.